Cadherin-16 anticorps

N° du produit ABIN6297294

Cet anticorps anti-Cadherin-16 est un anticorps Souris Monoclonal détectant Cadherin-16 dans IHC. Adapté pour Humain, Souris, Rat, Chien et Lapin.

Aperçu rapide pour Cadherin-16 anticorps (ABIN6297294)

Antigène: Cadherin-16 (CDH16)

Reactivité: Humain, Souris, Rat, Chien, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Cadherin-16 anticorps

Fonction: Mouse anti-Human/Mouse/Rat/Rabbit/Dog Cadherin 16 Antibody [IHC only]

Specificité: Cell surface with some cytoplasmic

Purification: Recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Immunogène: Recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: Cadherin-16

Sujet:

Target Description: This mAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Gene Symbol: CDH16///UNQ695///PRO1340

ID gène: 1014

UniProt: O75309